J.C. Philpot, known as “The Seceder,” resigned in 1835 from the Church of England and became a Strict & Particular Baptist. Defending the faith in 1861 with his message The True, Proper, and Eternal Sonship of the Lord Jesus Christ the Only Begotten Son of God, Philpot bluntly stated,
[W]e have little hope of convincing those who have drunk deeply into the spirit of error. The poison is already in their veins, vitiating in them all that once seemed like truth and simplicity.
As infidelity, when once it has got full possession of the mind, rejects the clearest evidences from positive inability to credit them, so error, when once it has poisoned the heart, renders it for ever afterwards, in the great majority of instances, utterly incapable of receiving the truth.