Since I am one of those Christians who struggle very much with despair and self-loathing because of sin, this devotion by Martin Luther really struck me right in the heart. I never considered this before as part of our Mortification of Sin. I pray God will use this in your heart as well for your edification.
by Martin Luther
21 He made Him who knew no sin to be sin on our behalf, so that we might become the righteousness of God in Him. 2 Corinthians 5:21 (NASB)
When you become aware of your sin and are frightened by it, you must not allow the sin to remain in your conscience. This would only lead to despair. Rather, just as your awareness of sin flowed to you from Christ, so you must pour your sin back on him to free your conscience.